"You Are the Placebo is a must-read for anyone who wants to experience optimal health in mind, body, and spirit. Dr. Joe Dispenza dispels the myth that our. You Are The Placebo teaches readers to use their own mind to have the same effect of a placebo: health benefits without drugs. The science. The Placebo effect is a pretty nutty phenomenon. Merely the *belief* that a pill (or surgery) will benefit you can lead to those results--even Download PDF.
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Online store for Dr. Joe Dispenza products, workshops, clothing, gifts and more.. from CDN$ 7 Used from CDN$ 1 New from CDN$ Is it possible to heal by thought aloneâ€”without drugs or surgery? The truth is that it happens more often than you might expect. In You Are the. Get Instant Access to You Are The Placebo: Making Your Mind Matter By Joe Dispenza #65d8b8. EBOOK EPUB KINDLE PDF. Read Download.
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All Rights Reserved. Rather than possessing a static anatomy, our bodies are seething with change, moment by moment. Our brains are on the boil, teeming with the creation and destruction of neural connections in every second. Joe teach- es us that we can steer this process with intention, assuming the powerful position of driver of the vehicle, rather than the passive role of passenger. The discovery that the number of connections in a neural bundle can double with repeat stimulation revolutionized biology in the s.
It earned its discoverer, the neuropsychiatrist Eric Kandel, a Nobel Prize. In this way, we can reshape our brains via the signals we pass through our neural network. In the same decade that Kandel and others measured neuro- plasticity, other scientists discovered that few of our genes are stat- ic. The majority of genes estimates range from 75 to 85 percent are turned off and on by signals from our environment, including the environment of thoughts, beliefs, and emotions that we cul- tivate in our brains.
One class of these genes, the immediate early genes IEGs , takes only three seconds to reach peak expression. IEGs are often regulatory genes, controlling the expression of hun- dreds of other genes and thousands of other proteins at remote sites in our bodies.
Joe is one of the few science writers to fully grasp the role of emotion in transformation. Negative emotion may literally be an addiction to high levels of our own stress hormones, like cortisol and adrenaline.
Both these stress hormones and relaxation hor- mones like DHEA and oxytocin have set points, which explains why we feel uncomfortable in our skin when we think thoughts or countenance beliefs that drive our hormonal balance outside of that comfort zone. This idea is at the very frontier of the scientific understanding of addictions and cravings. By changing your internal state, you can change your exter- nal reality.
But faced with the alternative, surgery, she decided to make an appointment. She received a few more treatments, during which the acupuncturist taught her how to manipulate a spot near her elbow if the pain recurred.
Hall needed the fix from time to time, but the problem mostly just went away. She was telling her carpal-tunnel story to a friend one day and recounted how the acupuncturist had climbed up on the table with her. Kaptchuk had divided people with irritable bowel syndrome into three groups.
In one, acupuncturists went through all the motions of treatment, but used a device that only appeared to insert a needle. Subjects in a second group also got sham acupuncture, but delivered with more elaborate doctor-patient interaction than the first group received. A third group was given no treatment at all. He was more interested in how the strength of the treatment varied with the quality and quantity of interaction between the healer and the patient — the drama, in other words.
Hall reached out to him shortly after she read the paper. The findings of the I. He argued that all three approaches unfold in a space set aside for the purpose and proceed as if according to a script, with prescribed roles for every participant. When Hall contacted him, she seemed like a perfect addition to the team he was assembling to do just that.
He even had an idea of exactly how she could help. In the course of conducting the study, Kaptchuk had taken DNA samples from subjects in hopes of finding some molecular pattern among the responses. When Hall analyzed the I. Those with the high-COMT variant had the weakest placebo responses, and those with the opposite variant had the strongest. These effects were compounded by the amount of interaction each patient got: For instance, low-COMT, high-interaction patients fared best of all, but the low-COMT subjects who were placed in the no-treatment group did worse than the other genotypes in that group.
They were, in other words, more sensitive to the impact of the relationship with the healer. The rs gene snippet is one of a group that governs the production of COMT, and COMT is one of a number of enzymes that determine levels of catecholamines, a group of brain chemicals that includes dopamine and epinephrine. Low COMT tends to mean higher levels of dopamine, and vice versa. Hall points out that the catecholamines are associated with stress, as well as with reward and good feeling, which bolsters the possibility that the placebome plays an important role in illness and health, especially in the chronic, stress-related conditions that are most susceptible to placebo effects.
The placebo effect has been plaguing their business for more than a half-century — since the placebo-controlled study became the clinical-trial gold standard, requiring a new drug to demonstrate a significant therapeutic benefit over placebo to gain F.
Whatever the reason, a result is that drugs that pass the first couple of stages of the F. The industry would be delighted if it were able to identify placebo responders — say, by their genome — and exclude them from clinical trials. That simple logic, however, may not hold up as Hall continues her research into the genetic basis of the placebo.
Indeed, that research may have deeper implications for clinical drug trials, and for the drugs themselves, than pharma companies might expect. The subjects were randomly divided into four groups, following standard clinical-trial protocol, and received a daily dose of either vitamin E, aspirin, vitamin E with aspirin or a placebo.
A subset also had their DNA sampled — which, Hall realized, offered her a vastly larger genetic database to plumb for markers correlated to placebo response.
Analyzing the data amassed during the first 10 years of the study, Hall found that the women with the low-COMT gene variant had significantly higher rates of heart disease than women with the high-COMT variant, and that the risk was reduced for those low-COMT women who received the active treatments but not in those given placebos. Among high-COMT people, the results were the inverse: Women taking placebos had the lowest rates of disease; people in the treatment arms had an increased risk.
These findings in some ways seem to confound the results of the I.